News Neuroscience

Semaglutide saps mice’s motivation to run

Preliminary results hint at a relationship between exercise and drugs like Ozempic and Wegovy

A white mouse runs on exercsise wheel. The background is green.

Mice voluntarily run on wheels, as this stock art shows. Mice on the drug semaglutide, sold as Ozempic and Wegovy, ran shorter distances on a wheel than mice not on the drug, a preliminary study shows.

GlobalP/Getty Images

By Laura Sanders

CHICAGO — Mice love to run. But not when they’re taking semaglutide, the diabetes and weight-loss drug sold as Ozempic and Wegovy.