An mRNA vaccine protected mice against deadly intestinal C. difficile bacteria

All laboratory mice given the new vaccine survived a highly lethal dose of the pathogen

Clostridioides difficile illustration

The deadly intestinal bacterial pathogen Clostridioides difficile has so far evaded attempts to devise an effective vaccine. Now, new research shows that an mRNA vaccine can protect mice against severe illness and death.

Clostridioides difficile is a notoriously nasty intestinal bug, with few effective treatments and no approved vaccines.